The applicability of computational chemistry in the evaluation and prediction of drug transport properties
作者:
Ulf Norinder [1]
;
Thomas Osterberg [2]
作者单位:
Pharmacia & Upjohn AB, Pharmaceutical Development, SE-112 87 Stockholm, Sweden
[1]
AstraZeneca R&D Sodertalje, Medicinal Chemistry, SE-151 85 Sodertalje, Sweden
[2]
关键词:
blood-brain barrier;Caco-2 cell membrane permeability;human intestinal absorption;log D;log K_s;log P;MolSurf;PLS
发布时间:
2013-11-21
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