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颜氏第三代立体视觉检查图在间歇性外斜视患者中的应用

Application of Yan's Random Dot Stereotest Version 3 in Patients with Intermittent Exotropia

摘要:

目的::探究颜氏第三代立体视觉检查图(YRDS3)在间歇性外斜视(IXT)患者中应用的临床特征与效果。方法::病例对照研究。连续收集2023年2—5月于北京同仁医院眼科中心确诊为IXT的患者(IXT组)和正位视患者(正位组)各90例,按年龄分为3~5岁、6~8岁和9~40岁3个亚组,受检者在就诊期间1个月内完成YRDS3各3次测试。YRDS3在IXT组和正位组中的可测试率差异比较采用卡方检验和Fisher精确检验,3次测试间的一致性用Bland-Altman法进行分析。结果::YRDS3在3~5岁组3次测试的可测试率分别为88.3%、93.3%和100.0%;6~8岁组3次测试的可测试率分别为96.7%、100.0%和100.0%;9~40岁组3次测试的可测试率均为100.0%。IXT组3次测试的可测试率分别为95.6%、100.0%和100.0%,正位组3次测试的可测试率分别为94.4%、95.6%和100.0%,组间可测试率差异均无统计学意义(均 P>0.05)。Bland-Altman显示正位组第2次与第1次测试一致性不佳,第3次与第2次测试一致性好,其差值平均值(MD)分别为0.03和0.00,95%一致性界限(LoA)分别为-0.11~0.17( P=0.001)和-0.04~0.04( P=0.320);IXT组测试一致性均好,其MD分别为0.02和0.01,95% LoA分别为-0.27~0.31( P=0.143)和-0.07~0.08( P=0.118),均在临床可接受范围内。正位组3个年龄亚组的立体视锐度95%参考值分别为158、67、60弧秒,IXT组3个年龄亚组的95%参考值分别为200、120、309弧秒。 结论::IXT患者近立体视受损,低于正常阈值。YRDS3在各年龄段的IXT患者中均可获得较高的可测试率,可为低龄儿童理解并接受,且儿童的可测试率随年龄的增长而提高。YRDS3在IXT患者中的测试一致性较好。

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abstracts:

Objective::To investigate the clinical characteristics and effects of Yan's Random Dot Stereotest Version 3 (YRDS3) in patients with intermittent exotropia (IXT).Methods::This was a case-control study. Totally 90 patients who were diagnosed with IXT (IXT group) and 90 patients diagnosed with orthophoria (orthophoria group) in Beijing Tongren Eye Center from February to May 2023 were continuously collected. They were divided into 3 subgroups according to age: 3-5 years old, 6-8 years old, and 9-40 years old. Participants completed 3 YRDS3 tests within one month during the visit. Chi-square test and Fisher exact test were used to compare the difference of the testability rate of YRDS3 between the IXT group and the orthophoria group. The Bland-Altman consistency test was used for the test consistency among three tests.Results::The testability rates of YRDS3 of the three tests were 88.3%, 93.3%, and 100.0% in the 3-5 years old group respectively. In 6-8 years old group, they were 96.7%, 100.0% and 100.0%, respectively. And in the 9-40 years old group, they were all 100.0% in the three tests. The testability rate of the three tests were 95.6%, 100.0% and 100.0% in IXT group respectively. The testability rates of the three tests were 94.4%, 95.6% and 100.0% in orthophoria group respectively. There was no significant difference of the testability rate between the IXT group and the orthophoria group (all P>0.05). Bland-Altman analysis showed that the test consistency was bad between the second and the first tests in orthophoria group, but good between the third and the second tests. The mean differences (MD) were 0.03 and 0.00, respectively. The 95% limits of agreement (LoA) were -0.11 to 0.17 ( P=0.001) and -0.04 to 0.04 ( P=0.320), respectively. The test consistency in IXT group were good, the MD were 0.02 and 0.01, respectively. 95% LoA were -0.27 to 0.31 ( P=0.143) and -0.07 to 0.08 ( P=0.118), which were within the clinically acceptable range. The 95% values of stereoacuity in the three age subgroups of the orthophoria group were 158 arcseconds, 67 arcseconds, and 60 arcseconds, respectively. And the 95% values of the age subgroups of the IXT group were 200 arcseconds, 120 arcseconds, and 309 arcseconds, respectively. Conclusions::The near stereopsis in patients with IXT is impaired below the normal threshold. YRDS3 has a high testability rate in patients with IXT of all ages, which can be understood and accepted well by young children. And the testability rate of children increases with age. YRDS3 has good test consistency in patients with IXT.

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作者: 赵逸阳 [1] 付晶 [1] 郝洁 [1]
栏目名称: 论著
DOI: 10.3760/cma.j.cn115909-20240110-00020
发布时间: 2024-10-15
基金项目:
国家自然科学基金 北京市科委科技计划 National Natural Science Foundation of China Program of Beijing Municipal Science & Technology Commission
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