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目的:探讨内镜下袖状胃成形术（ESG）治疗肥胖病的临床效果。方法:1例女性26岁患者，因“体质量进行性增加2年”于2022年10月20日入院，体质量指数（BMI）30.04 kg/m 2，体脂百分比39.2%，内脏脂肪等级为15。采用OverStitch SX内镜缝合系统进行ESG手术。 结果:患者手术顺利，术中出血约5 ml。术后第1天出院。术后两周行胃碘油造影见胃呈管状形态，术后6个月复查BMI为25.2 kg/m 2，体脂百分比32%，内脏脂肪等级：10，术后6月总体质量丢失率（%TBWL）为16%，多余体质量减少率（%EWL）为54.5%。 结论:ESG治疗肥胖性疾病可行有效。

Objective:To explore the clinical efficacy of endoscopic sleeve gastrectomy (ESG) in the treatment of obesity.Method:A 26 year old female patient was admitted on October 20, 2022 due to a progressive increase in weight for 2 years. Her body mass index (BMI) was 30.04 kg/m 2, body fat percentage was 39.2%, and visceral fat grade was 15. ESG was performed using the OverStitch SX endoscopic suture system. Result:The surgery was successful, with approximately 5 ml of intraoperative bleeding.The patient discharged on the first day after surgery. Two weeks after surgery, small bowel follow-through showed a tubular shape of the stomach. At 6 months after surgery, the BMI was 25.2 kg/m 2, body fat percentage was 32%, visceral fat grade was 10. The total body weight loss rate (%TBWL) at 6 months after surgery was 16%, and the excess weight loss rate (%EWL) was 54.5%. Conclusion:ESG is effective for the treatment of obesity.