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单克隆抗体药物抑制肿瘤血管新生机制的研究进展(文献综述)
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- Author:
- No author available
- Journal Title:
- JOURNAL OF RADIOIMMUNOLOGY
- Issue:
- 6
- DOI:
- 10.3969/j.issn.1008-9810.2013.06.038
- Key Word:
- No keyword available
Abstract： @@ 血管新生与肿瘤的发生、生长、转移密切相关[1].在过去的十年里我们对血管新生这一复杂过程的认识有了飞速的发展,此过程包括:内皮干细胞的迁移、内皮细胞的迁移和侵入、内皮细胞的增殖、内皮细胞在管状结构中的组织、循环系统的形成、血管的成熟、血管的退化.随着对这些过程和参与这些过程的分子的认识加深,导致了许多新的血管新生抑制剂的出现和发展[1-3].二十多年来对血管新生抑制剂的研究已取得巨大进展,发现了许多血管新生抑制剂,但一些抑制剂发挥作用的机制并不清楚.
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