You Position: Home > Paper
Clinical Relevance of the Changes on Selenium , GPX and CD94 in Peripheral Blood in Patients with RSA
( views:260, downloads:16 )
- Author:
- No author available
- Journal Title:
- JOURNAL OF RADIOIMMUNOLOGY
- Issue:
- 6
- DOI:
- 10.3969/j.issn.1008-9810.2013.06.051
- Key Word:
- 流产;自然;血硒;谷胱甘肽过氧化物酶;CD94
Abstract： 目的:检测原因不明反复自然流产(RSA)患者血硒、谷胱甘肽过氧化物酶(GPX)及外周血中CD94水平变化,探讨该类变化对反复自然流产发病中的作用.方法:采集RSA患者、正常妊娠妇女和非妊娠妇女(各35例)外周血检测硒、GPX与CD94含量.结果:RSA患者血硒、GPX水平均比正常妊娠妇女和非妊娠妇女呈现显著低下(P<0.01),CD94水平均亦比正常妊娠妇女和非妊娠妇女低(P<0.05).结论:血硒、GPX 与CD94在外周血中的低表达可能与反复自然流产的发病和病理生理过程有关.
- [1]王艳丽.反复自然流产患者外周血中CD94-含量相关性分析[J].2008,(34).
- [2]叶喜阳,张乃哲,付琳杰,等.反复自然流产患者血清及绒毛组织中一氧化氮含量检测的临床意义[J].2002,(5).
- [3]林其德,汪希鹏.原因不明复发性流产的病因病理生理机制与治疗研究进展[J].2007,(1).
- [4]李素媚.微量元素硒的临床应用新进展[J].2009,(7).
- [5]张群,胡雪梅.蜕膜NK细胞及其分泌的细胞因子与妊娠[J].2006,(4).
- [6]Szymanski W,Zachara BA,Dobrzynski W,etc.Blood selenium and glutathione peroxidases in miscarriage.[J].2001,108(3).
- [7]Kaya H,Ozkaya O,Sezik M.Serum malondialdehyde, erythrocyte glutathione peroxidase, and erythrocyte superoxide dismutase levels in women with early spontaneous abortions accompanied by vaginal bleeding.[J].2008,14(1).
- [8]Zachara B.A.,Wardak C.,Didkowski W.,etc.Changes in Blood Selenium and Glutathione Concentrations and Glutathione Peroxidase Activity in Human Pregnancy[J].1993,35(1).
- [9]Habib, Ksouri,Mondher, Zitouni,Wafa, Achour,etc.[Recurrent pregnancy loss related to immune disorders].[J].2003,154(4).