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Clinical Significance of Determination the Changes on Plasma Leptin Serum PRL, E2 and TSGF Levels After Operation in Patients with Breast Cancer
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- Author:
- No author available
- Journal Title:
- JOURNAL OF RADIOIMMUNOLOGY
- Issue:
- 6
- DOI:
- 10.3969/j.issn.1008-9810.2013.06.052
- Key Word:
- 乳腺癌;瘦素;垂体泌乳素;雌二醇;肿瘤特异性生长因子
Abstract： 目的:探讨乳腺癌手术治疗前后血浆leptin和血清PRL、E2和TSGF水平的变化及临床意义.方法:应用酶联免疫吸附试验法、电化学发光法、化学法对33例乳腺癌患者进行了手术治疗前后血浆leptin和血清PRL、E2和TSGF检测,并与35名正常健康人作比较.结果:乳腺癌患者手术治疗前血浆leptin和血清PRL、E2和TSGF水平均显著地高于正常人组(P＜0.01),经手术治疗3个月后与正常人组比较无显著性差异(P＞0.05),且血浆leptin水平和血清PRL、E2和TSGF水平呈显著正相关(r=0.6139、0.5821、0.4982,P＜0.01).结论:leptin和PRL、E2和TSGF的变化参与了乳腺癌的发生与发展.
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