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Clinical Significance of Determination of Changes on Serum IL-18, D-D and APN Levels After Treatment in Patients with Chronic Obstructive Pulmonary Diseases(COPD)
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- Author:
- No author available
- Journal Title:
- JOURNAL OF RADIOIMMUNOLOGY
- Issue:
- 6
- DOI:
- 10.3969/j.issn.1008-9810.2013.06.059
- Key Word:
- 慢性阻塞性肺疾病;白细胞介素-18;D-二聚体;脂联素
Abstract： 目的:探讨了COPD患者治疗前后血清IL-18、D-D和APN水平的变化及临床意义.方法:应用酶联法和生化法对40例COPD患者进行了治疗前后血清IL-18、D-D和APN检测,并与35名健康人作比较.结果:COPD患者在治疗前后血清IL-18、D-D和APN水平均非常显著地高于正常人组(P＜0.01),经治疗2周后则与正常人组比较无显著性差异(P＞0.05),且血清IL-18水平与D-D、APN水平呈显著正相关(r=0.5018、0.6134,P＜0.01).结论:检测COPD患者血清IL-18、D-D和APN水平的变化对了解病情、观察疗效和预后判定均具有一定的临床意义.
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