Abstract： Objective:To analyze the effects of nursing intervention under family empowerment model on the success rate, compliance and maternal mood of premature infants with breastfeeding.Methods:A total of 88 preterm parturients admitted to the Obstetrics and Gynecology Hospital of Fudan University from February 2015 to January 2023 were selected and divided into control group (routine nursing intervention) (43 cases) and observation group (nursing intervention under family empowerment mode) (45 cases) according to nursing methods.The scores of maternal feeding self-efficacy scale, breastfeeding knowledge questionnaire, compliance and self-rating Depression Scale (SDS) and self-rating Anxiety Scale (SAS) were compared between the two groups.Results:After intervention, the scores of maternal feeding efficacy and mastery of feeding knowledge in the observation group were significantly higher than those in the control group, and the differences were statistically significant( P<0.05).After intervention, the compliance rate of the observation group was higher, and the difference was statistically significant( P<0.05).After intervention, the SAS and SDS in the observation group were lower than those in the control group, and the differences were statistically significant( P<0.05). Conclusions:The nursing intervention under the family empowerment model is conducive to improving the maternal feeding efficiency and feeding knowledge, and the application effect is better in improving the maternal feeding compliance and psychological state.