Abstract： Objective To investigate the predictive value of glycemic gap in the conservative medicine treatment of symp-tomatic intracranial hemorrhage in stroke patients.Methods A retrospective analysis was conducted on 133 elderly stroke patients who received conservative drug treatment in Xuanwu Hospital,Capital Medical University from January 2021 to January 2023.Accord-ing to whether symptomatic intracranial hemorrhage occurred,they were divided into the occurrence group(33 cases)and the non-oc-currence group(100 cases),and relevant clinical data of the two groups were collected.Multivariate logistic regression was used to an-alyze the related factors affecting the occurrence of symptomatic intracranial hemorrhage,and ROC curve was drawn to analyze the pre-dictive value of glycemic gap on the occurrence of symptomatic intracranial hemorrhage.Results There were significant differences in age,drinking history,National Institutes of Health Stroke Scale(NIHSS)score,combined hypertension and glycemic gap between the two groups(P<0.05).Indicators with differences were substituted into logistic regression equations as independent variables,the results showed that age≥75 years old,drinking history,NIHSS score,accompanied by hypertension and glycemic gap were all inde-pendent risk factors for symptomatic intracranial hemorrhage in stroke patients receiving conservative drug treatment(P<0.05).ROC curve showed that the glycemic gap had a high predictive value for symptomatic intracranial hemorrhage in stroke patients(area under the curve was 0.898).Conclusion Glycemic gap is an influential factor for symptomatic intracranial hemorrhage in stroke pa-tients,and has a high predictive value for symptomatic intracranial hemorrhage in stroke patients.