Abstract： Baicalin(BA),a flavonoid extracted from the roots of Scutellaria baicalensis,has significant neuroprotective,anti-inflammatory,antioxidant,and anti-apoptotic properties,with a notable safety profile and low negative effects.BA has been ac-knowledged for its capacity to prevent and cure cognitive deficits and learning impairments linked to illnesses of the central nervous sys-tem.Simultaneously,sleep disorders(SD),which often occur along with cognitive dysfunctions,have shown improvement with BA therapy,but the exact reasons behind this improvement are not yet completely understood.This study presents a comprehensive over-view of the existing pharmacological knowledge on BA and examines its recent progress in treating cognitive deficits.The goal is to pro-vide fresh insights on how to effectively use BA and traditional Chinese medicine for addressing cognitive dysfunctions.