Abstract： Internal medicine teaching content is abstract,covering multiple disciplines,multiple systems,the traditional infu-sion teaching method is prone to the phenomenon of"doing its own thing"of each discipline,which is not conducive to the development and optimization of medical education.The common teaching ways include problem-based learning(PBL)teaching method and case-based learning(CBL)teaching method.With the development of information technology,internal medicine teaching has gradually entered the multidimensional interactive teaching model under the addition of"Internet+".The"Internet+"multidimensional interactive teach-ing combined with PBL and CBL teaching model has many advantages over the traditional teaching model.This paper intends to review the application status of the above two main teaching models in internal medicine teaching and explore the application significance and value of multidimensional interactive teaching model in internal medicine teaching under the background of"Internet+".