Abstract： Generalized anxiety disorder is one of the most common anxiety disorders in clinical practice,which seriously threatens the physical and mental health and quality of patients'life.Depression syndrome is a widely recognized name of generalized anxiety disorder.According to the aspects of etiology,pathogenesis and clinical manifestations,palpitation,lily disease or dirty and manic recorded in ancient literature are closely related to it.The common factors of the disease are deficiency of the body,compounded by the injury of seven feelings,the disease is in the brain,involving the liver,the heart,the spleen,the basic pathogenesis of the liver qi is not sparse,qi stagnation,depression and fire,damaging yin blood,blood does not nourish the heart,restless.Liver-depression of fire,phlegm-fire disturbance,deficiency of heart and spleen,deficiency of heart and gallbladder and qi,heart-kidney disjunction,etc.,are often witnessed.Chinese medicine treatment focuses on syndrome differentiation and treatment,mainly adopts traditional Chinese medicine such as classical prescription and experience prescription,combined with acupuncture,massage,Baduanjin and other non-drug therapies to regulate the body and spirit,which can significantly improve anxiety,especially increase efficiency and reduce toxicity,and improve the quality of life of patients.