Abstract： Objective To explore the characteristics of deficiency-excess syndrome elements of traditional Chinese medicine in patients with pulmonary sepsis,and analyze its impact on the prognosis of the disease.Methods A total of 128 patients with pul-monary sepsis in ICU of the hospital from 2018 Jan.to 2020 Jan.were involved in the research.According to the syndrome differ-entiation,they were divided into the deficiency and excess groups.The incidence of shock,28-day mortality,white blood cell count,procalcitonin(PCT),blood lactic acid and etiological results were compared between the two groups.Results There were 65 cases in the deficiency syndrome group and 103 cases in the excess syndrome group.The incidence of shock(23/42 vs.17/86,x2=7.830,P=0.005)and 28-day mortality(23.3％vs.41.5％,x2=6.270,P=0.012)in the deficiency group were signifi-cantly higher than those in the excess group.In the deficiency group,G+infection was lower than that in the excess group(24/37 vs.24/64),whereas G-infection(31/37 vs.40/64)was higher than that in the excess group,and the significant difference was found between the two groups(x2=5.087,P=0.024).The white blood cell count[(9.76±4.28 × 109)/L vs.(12.85±10.50 × 109)/L,t=-2.257,P=0.025]and blood lactic acid[1.90(1.59,2.63)vs.2.27(1.77,2.98),Z=1.382,P=0.044]in the deficiency group were significantly lower than those in the excess group.Conclusion The incidence of shock and mortality in the patients with deficiency syndrome of pulmonary sepsis were significantly higher than those in the patients with excess syn-drome.Reinforcing healthy Qi therapy should be run through the whole process of sepsis treatment.