Abstract： Objective To observe the Effect of Bushen Zhuyun Decoction(补肾助孕方)on endometrial receptivity and preg-nancy outcome in patients with recurrent spontaneous abortion.Methods A total of 100 patients with recurrent spontaneous abor-tion treated in the hospital from October 2019 to March 2021 were selected and divided into control group(50 cases)and test group(50 cases)according to random number table.The examination indexes of this study included TCM syndrome scores,men-strual condition score,endometrial receptivity related indexes and pregnancy outcome before and after treatment.Results During the study,3 patients in the control group were lost to follow-up,and 2 patients in the test group did not take medicine according to the prescribed test protocol during the treatment period.Finally,95 patients completed the study,including 47 patients in the control group and 48 patients in the test group.After treatment,the total effective rate,menstrual condition improvement and clini-cal pregnancy rate of the test group were better than those of the control group,and the TCM syndrome scores were decreased,with a statistically significant difference(P＜0.05).After treatment,endometrial thickness,morphology and blood flow distribution of the test group were significantly optimized,the resistance index(RI)was significantly reduced with statistical significance(P＜0.05)and there was no significant difference in perfusion index(PI)(P＞0.05).After follow-up,it was found that the clinical pregnancy rate was significantly higher and the number of pregnancy failures was lower in the test group than thsoe in the control group(P＜0.05).There was no significant difference in the incidence of adverse effects between the two groups(P＞0.05).Conclusion The study suggested that Bushen Zhuyun Decoction could improve TCM syndromes and improve clinical pregnancy rates in RSA patients.Therefore,the preconception intervention by Bushen Zhuyun Decoction could obviously promote endometri-um growth,increase endometrial blood flow perfusion and reduce the values of RI and PI,which verified that Bushen Zhuyun De-coction could improve endometrium receptivity for the treatment of RS A.