Abstract： Objective To investigate the clinical effect of nourishing Yin and removing blood stasis method on oligohydramnios in the third trimester of pregnancy.Methods Sixty patients with oligohydramnios in the third trimester of pregnancy admitted to the hospital from September 2021 to September 2022 were divided into the control group(30 cases)and the treatment group(30 ca-ses)according to the method of random number table.The control group was given routine treatment,and the treatment group was given the nourishing Yin and removing blood stasis method on the basis of the control group.Both groups were treated for 4 weeks,and were followed up until the end of delivery.The curative effect after 4 weeks of treatment,the amniotic fluid,placental blood perfusion situation and levels of sex hormones before and after 4 weeks of treatment,the scores of traditional Chinese medicine symptom before treatment and after 1 and 4 weeks of treatment,the neonatal asphyxia at the end of delivery and the pregnancy out-come during the followed up period of the two groups were compared.Results The total effective rate in the treatment group was 90.00％(27/30),higher than 66.67％(20/30)in the control group after 4 weeks of treatment(P＜0.05).Compared with those before treatment,after 1 and 4 weeks of treatment,the scores of traditional Chinese medicine symptoms of the two groups showed a gradually decreasing trend,and the scores of traditional Chinese medicine symptoms of the treatment group after 1 and 4 weeks of treatment were lower than those of the control group(P＜0.05).Compared with those before treatment,after 4 weeks of treatment,the levels of amniotic fluid index(AFI),serum estrogen(E2)and prostaglandin E(PGE)in the two groups increased,and those in the treatment group were higher than those in the control group(P＜0.05).The maximum systolic blood flow velocity of renal ar-tery/end diastolic blood flow velocity(S/D),umbilical artery S/D and level of serum progesterone(P)in the two groups de-creased,and those in the treatment group were lower than those in the control group(P＜0.05).The incidence of neonatal as-phyxia in the treatment group was 3.33％(1/30),lower than 23.33％(7/30)at the end of delivery in the control group(P＜0.05).The incidence of adverse pregnancy in the treatment group was 6.67％(2/30),lower than 26.67％(8/30)during the followed up period in the control group(P＜0.05).Conclusion The method of nourishing Yin and removing blood stasis could ef-fectively regulate the levels of sex hormones of patients with oligohydramnios in the third trimester of pregnancy,improve the amni-otic fluid,placental blood perfusion situation and traditional Chinese medicine symptoms,thereby reducing the occurrence of neo-natal asphyxia and improving the pregnancy outcome.The effect was significant.