Abstract： Objective To explore the rehabilitation effect of dredging Du meridian,supplementing brain and resolving phlegm method combined with acupuncture in acute ischemic stroke patients with dysphagia of phlegm and blood stasis blocking collateral syndrome.Methods A total of 112 acute ischemic strok epatients with dysphagia of phlegm and blood stasis blocking collateral syndrome were included in this study.The patients were divided into control group(56 cases)and traditional Chinese medicine group(56 cases)by random number table method.The patients in the control group were given pharyngeal muscle electrical stimu-lation,and those in the traditional Chinese medicine group were given pharyngeal muscle electrical stimulation combined with dredging Du meridian,supplementing brain and resolving phlegm method and acupuncture treatment.The changes of depression water test score(WST),Functional Oral Feeding Scale(FOIS)score,dysphagia Evaluation Scale(VFSS)and Standard Swallowing Function Evaluation Scale(SSA)score before and after treatment,the effect,complications,total scores of TCM syndrome before and after treatment and National Institutes of Health Stroke Scale(NIHSS),the changes of brain-derived neurotrophic factor(BDNF),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)and the score of quality of Life scale(Generic Quality of Life Inventory-74,GQOL1-74)before and after treatment were compared.Results Before treatment,WST score,FOIS score,VF-SS score,SSA score,total TCM syndrome score,NIHSS score,the levels of BDNF,IL-6 and TNF-α,GQOLI-74 score and oth-er indexes were not significant in two groups(P＞0.05).After treatment,WST score,FOIS score,VFSS score,SSA score,total TCM syndrome score,NIHSS score,the levels of BDNF,IL-6 and TNF-α,GQOLI-74 score and other indicators were all im-proved in two groups.And the above indexes in the traditional Chinese medicine group were better than those in control group(P＜0.05).The total effective rate of the traditional Chinese medicine group was higher than that of control group,and the com-plication rate was lower than that of control group(all P＜0.05).Conclusion The combination of dredging Du meridian,supple-menting brain and resolving phlegm method with acupuncture can better promote the rehabilitation of patients with dysphagia of phlegm and blood stasis blocking collateral syndrome in acute ischemic stroke.The treatment effect of the patient has been im-proved,with improved swallowing function,neurological function,and quality of life.In addition,the patients'complication rate is low,making it relatively safe and reliable,which is worthy of applying.