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The diagnostic value of neutrophil/lymphocyte ratio combined with nutritional risk screening in senile pa-tients with sarcopenia
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- Author:
- No author available
- Journal Title:
- Military Medical Journal of Southeast China
- Issue:
- 3
- DOI:
- 10.3969/j.issn.1672-271X.2023.03.004
- Key Word:
- 老年患者;肌少症;中性粒细胞/淋巴细胞比值;影响因素;elderly patients;sarcopenia;neutrophil-to-lymphocye ratio;factors affecting
Abstract： 目的 探究中性粒细胞/淋巴细胞比值(NLR)及营养风险筛查(NRS2002)对老年患者肌少症的诊断价值.方法 回顾性分析江苏省中医院老年病科收治的160例老年住院患者的临床资料,依据是否为肌少症分为肌少症组75例和非肌少症组85例.收集患者临床资料,采用单因素、多因素非条件性Logistic回归分析肌少症发生的影响因素,绘制受试者工作特征(ROC)曲线分析其诊断价值,分析肌少症患者NLR水平与NRS2002评分的相关性.结果 单因素分析显示,肌少症组与非肌少症组年龄、NRS2002评分、握力、步速、骨骼肌质量指数(ASMI)、血清白蛋白(Alb)、血红蛋白(Hb)及NLR比较,差异有统计学意义(P＜0.05);多因素非条件性Logistic回归分析显示,年龄(95％CI:1.036～1.126)、NRS2002(95％CI:1.043～2.093)和NLR(95％CI:1.006～1.373)是老年患者发生肌少症的影响因素;NLR联合NRS2002对患者发生肌少症预测的ROC曲线下面积(AUC)为0.730,敏感度为0.835,特异度为0.533;肌少症患者NLR水平与NRS2002评分呈正相关(r=0.439,P＜0.001).结论 NLR水平及NRS2002评分是老年患者发生肌少症的影响因素,NLR联合NRS2002对老年患者发生肌少症具有一定预测价值.
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