You Position: Home > Paper
Mornitoring drug resistance of meticillin-resistant Staphylococcus aureus
( views:143, downloads:0 )
- Author:
- No author available
- Journal Title:
- JOURNAL OF NANJING MILITARY MEDICAL COLLEGE
- Issue:
- 4
- DOI:
- No doi available
- Key Word:
- 耐甲氧西林葡萄球菌;抗菌药物;耐药率
Abstract： 目的:监测临床分离的耐甲氧西林葡萄球菌的耐药性,并探讨对耐药菌感染的治疗策略.方法:对临床分离的152株葡萄球菌用表型检测的琼脂筛选法检测耐甲氧西林葡萄球菌(MRS),用Kirby-Bauer琼脂扩散法做药敏试验.结果:筛选出MRS 79株,检出率为51.97%,其中耐甲氧西林金黄色葡萄球菌(MRSA)为60.00%,耐甲氧西林凝固酶阴性葡萄球菌(MRC-NS)为41.79%.MRS对万古霉素、利复平和阿米卡星的耐药率较低,对其他抗生素耐药率较高;甲氧西林敏感葡萄球菌(MSS)除对青霉素的耐药率较高外,对其他抗生素的耐药率显著低于MRS.结论:MRS具有多重耐药性,应长期进行耐药性检测;MRS重症感染应首选糖肽类抗生素万古霉素治疗.
- [1]T L, Smith,M L, Pearson,K R, Wilcox,etc.Emergence of vancomycin resistance in Staphylococcus aureus. Glycopeptide-Intermediate Staphylococcus aureus Working Group.[J].1999,340(7).
- [2]倪语星,洪秀华.细菌耐药性监测抗感染治疗[M].2002.
- [3]马纪平,苏建荣,靳景图.耐甲氧苯青霉素葡萄球菌[J].1996,(3).
- [4]A M, Strandén,K, Ehlert,H, Labischinski,etc.Cell wall monoglycine cross-bridges and methicillin hypersusceptibility in a femAB null mutant of methicillin-resistant Staphylococcus aureus.[J].1997,179.
- [5]夏培元.耐甲氧西林金黄色葡萄球菌的耐药机制及其治疗药物的研究进展[J].1999,(4).