You Position: Home > Paper
Application of leucocyte filter of modified fiberglass membrane
( views:146, downloads:4 )
- Author:
- No author available
- Journal Title:
- JOURNAL OF NANJING MILITARY MEDICAL COLLEGE
- Issue:
- 4
- DOI:
- No doi available
- Key Word:
- 白细胞;血小板;过滤器
Abstract： 目的:为了去除浓缩血小板制剂中的白细胞,减少血小板输注无效症的发生率.方法:使用丙烯酸类的聚合物,固化在白细胞过滤器的膜表面,使膜的电位性正好吸附体积大的白细胞,而不吸附体积小的血小板.结果:70例次试验,过滤一个机采治疗量或10个单位手工法制备的浓缩血小板,能够滤除99.9%白细胞,血小板回收率大于90%.27例血液科病人输注浓缩血小板制剂,血小板输注无效率15%(4/27例),对照组血小板输注无效率50%(10/20例).结论:改性后的白细胞过滤器能用于浓缩血小板制剂的滤除,防止反复输注产生的血小板输注无效.
- [1]M. MASSE,C. NAEGELEN,N. PELLEGRINI,etc.Validation of a simple method to count very low white cell concentrations in filtered red cells or platelets[J].1992,32(6).
- [2]Riggert, J.,Simson, G.,Dittmann, J.,etc.Prestorage Leukocyte Depletion with In-Line Filtration of Whole Blood in Comparison with Blood Component Leukocyte Depletion[J].1995,69(3).
- [3]金洁,林修基.应用过滤器去除白细胞的血小板悬液输注及预防白细胞同种免疫反应[J].1993,014 (3).
- [4]Masaki Miyamoto,Shigeru Sasakawa,Yoshihide Ishikawa,etc.Leukocyte-Poor Platelet Concentrates at the Bedside by Filtration through Sepacell-PL[J].1989,57(3).
- [5]阎石,韩平.血小板输注无效的临床问题[J].1993,014 (12).