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Clinical significance in determination of changes in serum hs-CRP,cTnI and CK-MB in patients with unstable angina
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- Author:
- No author available
- Journal Title:
- JOURNAL OF NANJING MILITARY MEDICAL COLLEGE
- Issue:
- 4
- DOI:
- No doi available
- Key Word:
- 不稳定型心绞痛;超敏C反应蛋白;心肌肌钙蛋白Ⅰ
Abstract： 目的:探讨不稳定型心绞痛(UA)患者血清hs-CRP、cTnI及CK-MB测定的临床意义.方法:分别用免疫透射比浊法、夹心ELISA法及免疫抑制法测定63例UA患者和40例稳定型心绞痛(SA)患者血清hs-CRP、cTnI及CK-MB含量.结果:UA患者血清hs-CRP含量为(6.34±1.69)mg/L,与SA组(2.21±0.96)mg/L及健康组(1.10±0.64)mg/L相比较有极显著性差异(P＜0.01);UA患者血清cTnI含量为(8.60±8.34)μg/L,与SA组(2.47±1.79)ug/L及对照组(1.95±1.94)μg/L相比较有极显著性差异(P＜0.01);3组比较,各组患者血清CK-MB含量差异不显著(P＞0.05).结论:UA患者存在微小心肌损伤,炎症反应是UA一个重要发病因素,cTnI是判断微小心肌损伤特异且敏感的指标,hs-CRP在UA发病机制中有重要意义.
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