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Changes of serum neuron-specific enolase level in newborns with hypoxic-ischemic encephalopathy
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- Author:
- No author available
- Journal Title:
- JOURNAL OF NANJING MILITARY MEDICAL COLLEGE
- Issue:
- 4
- DOI:
- No doi available
- Key Word:
- 新生儿;缺氧缺血性脑病;神经元特异性烯醇化酶
Abstract： 目的:研究新生儿缺氧缺血性脑病(HIE)患者血清中神经元特异性烯醇化酶(NSE)的含量变化及临床意义.方法:采用酶联免疫吸附法(ELISA)对39例HIE患儿在起病第1,3,7天血清NSE水平进行了动态测定.结果:HIE患儿血清中NSE浓度明显高于对照组(P＜0.05),随着HIE临床分度的增加,NSE的含量显著升高.结论:血清NSE水平测定可作为早期判断HIE脑损伤程度和预后的生化指标.
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