Abstract： Objective To explore the efficacy of modified pathway laparoscopic surgery on cervical cancer and the effect on its serum indicators and prognosis.Methods 106 patients with cervical cancer were selected and divided into 2 groups ac-cording to different laparoscopic surgical pathways.Among them,50 cases in the study group were operated by modified posterior LRH,while 56 cases in the control group were operated by traditional LRH,and the clinical efficacy of the 2 groups was com-pared.Results There was no difference in operation time and number of lymph node dissection between the two groups(P＞0.05),while intraoperative bleeding and postoperative hospital stay in the study group were better than that in the control group(P＜0.05);There was no difference in the incidence of postoperative complications between the 2 groups(P＞0.05);The in-flammatory indexes of the 2 groups were elevated compared with that before operation,and it was more so in the control group(P＜0.05);At 1 year postoperatively,total survival rate and recurrence rate were not different(P＞0.05).Conclusion Modified pathway laparoscopic surgery has better efficacy for patients with cervical cancer,which not only reduces intraoperative bleeding and inflammatory reaction,but also does not affect the incidence of postoperative complications and prognosis,which is worthy of clinical promotion and application.