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梓醇抗氧化作用机制的研究进展
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- Author:
- No author available
- Journal Title:
- Tianjin Pharmacy
- Issue:
- 2
- DOI:
- 10.3969/j.issn.1006-5687.2024.02.018
- Key Word:
- 梓醇;地黄;自由基;抗氧化;氧化应激;作用机制
Abstract： 梓醇作为天然抗氧化剂,其抗氧化作用对生物体发挥重要保护作用,尤其在治疗糖尿病、肿瘤、神经损伤等疾病有明显作用且已被研究证实.通过搜索中国知网(CNKI)、万方数据库、Pubmed、Web of Science等中英文数据库,整理近年国内外对梓醇的抗氧化机制研究成果,总结梓醇抗氧化作用的研究现状.研究发现,梓醇可以直接捕捉和中和自由基,阻止其对细胞和组织的氧化损伤.其次,梓醇还通过激活抗氧化酶系统,增强细胞内的抗氧化能力.此外,梓醇能调节氧化应激相关的信号通路,抑制氧化应激引发的炎症反应,从而减少氧化损伤的发生.这些机制共同作用使得梓醇成为一种具有潜力的抗氧化剂,并且在预防癌症、心血管疾病、神经退行性疾病等发挥重要作用.因此梓醇在医药业的开发和利用有待评估和深入挖掘.
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