Abstract： Objective Study on the effects of clove oil combined with minocycline on pulp vitality,pain level,and inflammatory factors in patients with reversible pulpitis.Methods A total of 126 patients with reversible pulpitis admitted to the Xuchang Central Hospital were selected.63 patients treated with minocycline combined with clove oil were selected as the combined group,and 63 patients treated with clove oil alone were selected as the single group.The pulp vitality,pain degree,inflammatory factors and curative effect of the two groups were compared.Results After treatment,the test results of pulp vitality cold diagnosis method in the combined group were better than those in the single group,the difference was statistically significant(P<0.05);the test results of pulp vitality in the combined group were better than those in the single group,the differences were statistically significant(P<0.05);the overall pain degree of the combined group was better than that of the single group,the difference was statistically significant(P<0.05);the levels of inflammatory factors in the combined group were lower than those in the single group,the differences were statistically significant(P<0.05).The total effective rate of the combined group was higher than that of the single group,the difference was statistically significant(P<0.05).Conclusion The minocycline combined with clove oil in patients with reversible pulpitis can enhance the vitality of dental pulp through cold and hot diagnostic methods,reduce pain,and reduce the influence of inflammatory factors.