Abstract： Under the perspective of supply-side reform,Nanjing Medical University focuses on the require-ments for training undergraduate pharmacy talents who are proficient in both medicine and pharmacology in the new era.Centered around a student-oriented approach(I),the university explores and practices the reform of the undergraduate pharmacy talent training system,"I-SPARK,"through five aspects:scientific research promoting teaching(S),patient-centered humanistic quality cultivation(P),assurance system of cooperation education(A),research and training bases(R),and keen sense of patriotism and responsibi-lity(K),and achieves favorable outcomes.