Abstract： Hornet stings are relatively common in clinical work,and the clinical manifestations of patients may only show localized swelling and pain,but some patients also experience multiple organ failure.There-fore,timely identification and early treatment of critically ill patients with hornet stings are of great clinical sig-nificance.We firstly reviewed the clinical data of five patients with hornet stings,and summarized the clinical manifestations of patients after hornet stings in this paper,then analyzed the risk factors of critical condition to provide clinical references.