Abstract： Disruptions in circadian rhythms such as work,meal times,social jet lag and insufficient sleep can increase the risk of type 2 diabetes mellitus(T2DM).Food signals are factors that cause peripheral circadian oscillations and regulate circadian rhythms,playing an important role in human tissue metabolism.Time-restricted eating(TRE)is an emerging dietary intervention strategy that intervenes in glucose metabolism by controlling daily eating time,driving circadian oscillations of circadian clock genes and body energy metabolism.This article reviews the research progress of TRE and T2DM under circadian rhythm.