Abstract： A 31-year-old female was admitted with complaints of redness and pain in her both eyes for three weeks.She was once diagnosed with iridocyclitis in the other hospital with normal baseline intraocular pressure(IOP),and was treated with topical corticosteroids.She was infected with COVID-19 over 2 months prior to the onset of ocular symptoms and took oral moxifloxacin(400 mg once a day)for 6 days over 1 month ago.Her best corrected visual acuity was 1.0 in her right eye and 0.8 in her left eye.Slit lamp biomicroscopy showed transparent cornea,1+ pigmented keratic precipitates,1+ pigments in the anterior chamber without posterior synechia of the iris,round pupils with a diameter of 3 mm and sensitive to light,and transparent lens in both eyes.Fundus examination was unremarkable.Her IOP was 36 mmHg and 33 mmHg in her right and left eye,respectively.The results of rheumatoid factors were within normal range.Gonioscopy revealed open angles with heavy pigmentation at the trabecular meshwork(Grade Ⅳ)in both eyes.She was diagnosed with bilateral acute depigmentation of iris(BADI)and corticosteroid-induced ocular hypertension.After the corticosteroid was tapered,her IOP gradually stabilized.It must be kept in mind that we should inquire about the history of using fourth-generation quinolones when considering BADI.Simultaneously,it is essential to differentiate BADI it from iridocyclitis and pigment dispersion syndrome(pigmentary glaucoma).