Abstract： A 36-year-old woman presented with decreased vision in both eyes for 2 years after cataract surgery,and the vision loss was more obvious in the right eye.The patient underwent phacoemulsification combined with intraocular lens(IOL)implantation in the left eye and right eye at the age of 32 and 34 years,respectively.The best corrected visual acuity was 1.0(+12.25/-2.00×165°)for the right eye and 0.8(+1.25/-1.25×20°)for the left.Slit lamp examination showed:the diameter of both corneas was rather large;the pupils were slightly irregular and insensitive to mydriatic drugs;there is patchy atrophy of the iris with iridodonesis,and the intraocular lens was displaced downward.Ultrasound biomicroscopy(UBM)examination:the iris of both eyes is slightly posteriorly concave,the attachment point of the iris root is located posteriorly,the ciliary body is thin and small,and the scleral spur is not obvious.The patient was diagnosed with bilateral IOL dislocation and anterior segment dysgenesis(anterior macrophthalmia).Based on the patient's surgical history,the patient had had a Toric IOL implanted in her right eye,so she underwent anterior segment vitrectomy and scleral suture fixation of the original IOL successfully.Three weeks after the surgery,her uncorrected visual acuity was 1.0 in the right eye.For patients with IOL dislocation,we should first analyze the causes of IOL dislocation.At the same time,keep the concept of refractive cataracts in mind and make preoperative plan according to patients'eye condition.