Abstract: Acne vulgaris is a clinically common chronic inflammatory skin disease.Currently,severity grading and efficacy assessment in acne vulgaris mainly rely on dermatologists'clinical experience.In recent years,skin imaging techniques have raised great attention in the diagnosis and treatment of various skin diseases,owing to their non-invasive,real-time,objective and reproducible properties.This review summarizes the progress in application of various skin imaging techniques,including dermoscopy,reflectance confocal microscopy,optical coherence tomography and high-frequency ultrasound imaging,in the research of acne vulgaris,aiming to provide new ideas for basic research of acne vulgaris,as well as its clinical diagnosis and assessment of therapeutic efficacy.