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Background:Ulcerative colitis(UC)is a chronic and nonspecific intestinal inflammatory disease and its pathogenic mechanism has not yet been clarified. Intestinal mucosal immune function disorder may play a key role in the pathogenesis of UC. Aims:To investigate the effects of Wumeiwan on expressions of δ-opioid receptor(DOR),β-arrestin1 and Bcl-2 in rats with colitis. Methods:Fifty-six Sprague-Dawley rats were randomly divided into model group,Wumeiwan group, mesalazine group and blank group. Rats in model group,Wumeiwan group and mesalazine group were administered intrarectally with 5

作者:张丽娟;陈小艳;范恒;段雪云

来源:胃肠病学 2015 年 8期

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| 浏览:176 | 下载:40
作者:
张丽娟;陈小艳;范恒;段雪云
来源:
胃肠病学 2015 年 8期
标签:
结肠炎,溃疡性 受体,阿片样,δ 抑制蛋白 基因,bcl-2 乌梅丸 Colitis,Ulcerative Receptors,Opioid,delta Arrestin Genes,bcl-2 WUMEI PILL
Background:Ulcerative colitis(UC)is a chronic and nonspecific intestinal inflammatory disease and its pathogenic mechanism has not yet been clarified. Intestinal mucosal immune function disorder may play a key role in the pathogenesis of UC. Aims:To investigate the effects of Wumeiwan on expressions of δ-opioid receptor(DOR),β-arrestin1 and Bcl-2 in rats with colitis. Methods:Fifty-six Sprague-Dawley rats were randomly divided into model group,Wumeiwan group, mesalazine group and blank group. Rats in model group,Wumeiwan group and mesalazine group were administered intrarectally with 5

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