Objective To explore the correlations between effects in schizophrenics treated with clozapine.Method It was estimated for PANSS at baseline and 28th day as well as for serum clozapine level at 29th day in 66 schizophrenics receiving clozapine monotherapy.Results (1)There was all statistically significant positive correlations between 6 factors of TESS without coincident items;(2)Of 54 correlations between 6 factirs of TESS and 9 subtracting score rates of PANSS subscales.only 6 arrived statistically significant level;(3)Of 23 correlations between 9 subtracting score rates of PANSS subscales without coincident items, only 9 were statistically significant.Conclusion The same root correlation hypothesis in a narrow sense would be utility in future pharmacology.

作者：喻东山；张心保；蒋晓军；孙旦晖；肖红；张石宁

来源：中国临床康复 2002 年 6卷 21期