Introduction::Myiasis is an infestation of the tissues and organs of living vertebrates and humans by fly larvae, usually those belonging to the Calliphoridae family. The larvae feed on the host’s necrotic or living tissue.Case presentation::On mucocutaneous examination, the patient had multiple sinus tracts covered with purulent necrotic slough, and cylindrical maggots were crawling out of and around the areas of slough. The patient was diagnosed with wound myiasis caused by Cochliomyia hominivorax. Turpentine oil flushes and oral ivermectin were prescribed. Discussion::Cutaneous myiasis can be papular, pustular, furuncular, and nodular. It is more common in people who have poor hygiene and intimate contact with domestic animals, such as people living in rural areas and tropical/subtropical countries. The chief aim of management is to remove the maggots as soon as possible, kill them to prevent maturation, promote wound healing, and prevent development of secondary complications.Conclusion::In the current case, the patient’s poor nursing and personal care and low socioeconomic condition predisposed her to secondary wound infection and maggot infestation. Such cases require prompt care to prevent secondary infection and septicemia.

报道1例口呼吸患者口腔内蝇蛆病的病例,回顾分析疾病的发生发展,为临床蝇蛆病的预防和处置提供参考.

对本院住院的2例人皮肤蝇蛆感染患者体内分离的蝇蛆虫体进行病原形态学鉴定,结果显示,病例1感染蝇蛆为皮蝇科皮蝇属1龄幼虫,取出虫体后包块消失,治疗有效;病例2感染蝇蛆为麻蝇科污蝇属3龄幼虫,确诊后病人要求出院而无跟踪治疗.

目的 提高对蝇蛆病的认识.方法 回顾性分析首都医科大学附属北京友谊医院收治的4例皮肤蝇蛆病、鼻腔蝇蛆病和胃肠蝇蛆病确诊病例,并结合文献报道分析蝇蛆病的临床表现及其防治.结果 蝇蛆病常为偶然寄生,治疗以去除蝇类幼虫为主.结论 北京存在多种蝇蛆散发病例,患者常为流动人口.

报道1例输入性疖肿型皮肤蝇蛆病,并对致病瘤蝇的线粒体细胞色素C氧化酶亚基Ⅰ(COⅠ)基因序列进行分析.患者女,33岁.患者于1个月前去非洲加纳和喀麦隆两地,期间未采取任何防蚊措施,且有室外晾晒衣物经历.皮肤科检查:左上臂内侧和左侧胸部外侧各见一疖性隆起,直径1 ～2cm,鲜红色,边缘不规则,触之较硬,皮损表面中央有小孔.形态学观察显示皮损处挤出的虫体疑似为蝇蛆.PCR扩增虫体COⅠ基因片段获得650 bp左右的产物,测序后经BLAST比对分析显示,该产物与喀麦隆2010年分离的嗜人瘤蝇COⅠ基因FR719158.1亲缘关系最近,序列相似性为99.84％,在系统进化树上聚集在一起.综合患者的临床特征、旅行史和致病瘤蝇的序列分析结果,确认该病例为嗜人瘤蝇导致的输人性疖肿型皮肤蝇蛆病.

患儿,男性,6岁.出生于西北,1979年5月到沪,6月起先感下腹部发胀,继之出现左下腹部疼痛,但无红肿,二天后症状消失.

黑角一胃蝇(Gastrophilus nigricornis)第一期幼虫自然感染所致人体皮肤蝇蛆病的报告,仅见于姚氏等于1965年报告1例,我们于1977年5月中旬在新疆和布克赛尔蒙古自治县和什托洛盖地区偶获该蝇一期幼虫,经医科院寄研所审核为黑角胃蝇一期幼虫.

患者女,23岁,于1985年9月右股外侧皮肤发生灼痛,如生疖疮痒.局部红、硬,如核桃大.